The Dual-Use Research of Concern (DURC) Committee reviews all research activities that produces knowledge, technologies or products that could pose a significant public health threat if they fell into the wrong hands, as required by the United States Government Policy for Institutional Oversight of Life Sciences Dual Use Research of Concern (2014) and University policy. To meet the definition of ‘DURC,’ the research must involve one of 15 agents/toxins of concern (including botulinum neurotoxin) and involve one of 7 experimental effects of concern. Study teams indicate whether their project utilizes botulinum toxin (the only DURC agent permitted at Rush) in the Master Project under Question 7.0 of the Project Specific Information section.